Macer Floridus is the alleged pseudonym of Odo de Meung, a French cleric and physician who lived during the 11th century and was the presumed author of the herbal poem De Viribus Herbarum (On the properties of plants). The use of "Macer" alludes to the Roman poet, Aemilius Macer (16 B.C.), who authored a poem on remedies for those afflicted with wounds from poisonous serpents. The herbal, commonly referred to as the Macer Floridus, was written in Latin hexameter verse and presented the medicinal uses of plants. The rhyming verse aided doctors and apothecaries in memorizing medicinal recipes and treatments, which made the herbal popular among those who practiced medicine during the Middle Ages.

The Macer Floridus is recognized as a signal of revival in botanical interest following the Dark Ages, so named for the lack of recordkeeping during this time. Though not derived from personal observation, the Macer Floridus was assembled from such sources as Naturalis Historia by Pliny the Elder (23–79), the Greek physicians Pedanios Dioscorides (40–90) and Galenos of Pergamon (130–201), as well as the gardening manual Hortulus by the Benedictine poet and botanist Walahfrid Strabo (808–849).

On 9 May 1477 printer Arnaldus de Bruxella issued the first print edition of De Viribus Herbarum, which included 77 plants and their medicinal uses. A second edition was printed in Milan in 1489. An illustrated edition became available in the year 1500 and presented 66 wood-cut plant illustrations.